The Fraud of Cancer Research

Researchers are fabricating their findings to create the illusion of positive findings, instead of publishing their actual results, for the continuation of their steady stream of funding and grants.


“That the cartel’s medical monopoly has created a climate of bias in our educational system in which scientific truth is often sacrificed to vested interests.”— Edward Griffin

There was a bombshell in science journal Nature recently (Nature 483, 531–533-29 March 2012) about cancer research published in the leading peer-reviewed journals of the world. Authors of the paper, C Glenn Begley and Lee Ellis, were unable to replicate the results of 47 of the 53 (89%), studies examined. Begley stated in the paper: “These are the studies the pharmaceutical industry relies on to identify new targets for drug development, but if you’re going to place a $1 million or $2 million or $5 million bet on an observation, you need to be sure it’s true. As we tried to reproduce these papers we became convinced you can’t take anything at face value.”

Simply put, researchers are fabricating their findings to create the illusion of positive findings, instead of publishing their actual results, for the continuation of their steady stream of funding and grants. Based on such research papers, millions of hapless patients are led up the garden path to hell after spending all their life’s savings!

The Mayo Clinic, in 2009, concluded that data about harnessing the immune system to fight cancer had been fabricated, resulting in the retraction of 17 papers in nine research journals. Cancer research in the United States needs to be scrutinised. It is mainly money-driven and based on developing new drugs. Begley writes: “Fifty-three papers were deemed ‘landmark’ studies. It was acknowledged from the outset that some of the data might not hold up, because papers were deliberately selected that described something completely new, such as fresh approaches to targeting cancers or alternative clinical uses for existing therapeutics. Nevertheless, scientific findings were confirmed in only 6 (11%) cases. Even knowing the limitations of preclinical research, this was a shocking result.”

The final recommendation of the authors, at the end of the paper, is worth repeating verbatim here: “However, it is important to remember that patients are at the centre of all these efforts. If we in the field forget this, it is easy to lose our sense of focus, transparency and urgency. Cancer researchers are funded by community taxes and by the hard work and philanthropic donations of advocates. More importantly, patients rely on us to embrace innovation, make advances and deliver new therapies that will improve their lives. Although hundreds of thousands of research papers are published annually, too few clinical successes have been produced given the public investment of significant financial resources. We need a system that will facilitate a transparent discovery process that frequently and consistently leads to significant patient benefit.”

I must have written more than a dozen papers in the past about this ground reality. All that I earned was the wrath of the cancer lobby. We have a moral responsibility here. We are dealing with human life and cancer is probably the cruellest disease. What surprised me all these years is how we have been accepting chemicals and radiation in cancer treatment knowing well that such treatments also destroy healthy cells.

What would happen to the patient at the end of the day whose immune system cells are as damaged as the cancer cells? Have we ever given a thought to this human aspect of cancer treatment? One of the greatest brains in biology, a Nobel Laureate, Albert Szent-Györgyi, wondered how cancer treatment could be developed as the cancer cell works exactly like a normal cell. His concern was to develop a drug that kills the cancer cells and not the healthy immune body cells. In fact, cancer treatment does destroy all fast-dividing cells; the bone marrow and the immune cells do just that. How can anyone expect to heal a patient by destroying his immune system? Would any of you like to get on to a plane which is sure to crash 89% of the time? That is cancer treatment today!

“Everyone should know that most cancer research is largely a fraud and that the major cancer research organisations are derelict in their duties to the people who support them.”— Dr Linus Pauling (Twice Nobel Prize winner)

Professor Dr BM Hegde, a Padma Bhushan awardee in 2010, is an MD, PhD, FRCP (London, Edinburgh, Glasgow & Dublin), FACC and FAMS.

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    COMMENTS

    dinesh doshi

    7 years ago

    Iam self styled Doctor of URINE THERAPY, because there is no college or course for urine therapy course.I am practicing for 25 years.Recently a 60 years old patient of NONHODGKIN'S LYMPHOMA was indiecrtly advise to go home and wait for death. I was contacted to try as there was nothing to lose.Those who do not belive in urine therapy will say that diagnosis was wrong. i accompanied the patient to a very very big hospital and had discussion with the doctor. he asked what the scientific proof? I told him I am an ordinary man. I do not charge consultaton fee. But if you can refer me a patient who will not live 30 days under any circumstances and if he shows SUBSTANTIAL improvement in 10 days, will you consider this scientific? He was mum
    Dinesh Doshi, Mumbai +919619439665

    Dekho ji.com

    7 years ago

    This is nothing new. Max corruption occurs in this medical field because people's lives are most precious and all companies want to make huge profits at the cost of people's lives. So, fudge the data, publish some fake research articles in newspapers / journals and get the medicine onto the markets quickly before the fake lies are exposed. By the time, the fakes are detected, they would have made crores of Rs. Human beings have now become guinea pigs for these medical MNC companies.

    suresh pathak

    7 years ago

    Dr Hegde,
    The article does point out certain relevant issues .But this should not be forgotten that all research in the field of finding out therapeutically effective new chemical entities is a tortuous journey through a blind alley. Having spent several millions and a time spanning years ,one might land up at an NCE which is most effective but full of deterrent adverse effects which throws all investment go down the drain . And hence no research will ever be undertaken without a steady stream of funds being guaranteed.
    Compromise on moral ground with reporting and other procedures is akin to corruption and compromises in any other walk of life and may not be generalized.
    Rather a stiffer control system needs to be worked out with overseeing agencies .
    Further ,I beleive all research in the Cancer field has'nt gone waste . The median survival of patients ,and quality of life has tremendously improved which can be confirmed from any medical / surgical /radiation Oncologist with long years of experience .

    Suresh Pathak
    [email protected]

    Suiketu Shah

    7 years ago

    Great article.Thanks a lot Dr Hegde.

    Biomimicry: The science of learning from nature
    Respect nature as your mother and learn from her; if you abuse nature, she will kick you in the teeth! Long live mankind learning from nature as our Indian scientists of yore did
     
    “When one tugs at a single thing in nature, we find it attached to the rest of the world”— John Muir      
               
    I keep reminding the readers about our wrong efforts at learning science by teaching nature a lesson or two. We could have a better science by understanding nature’s working better, as been my hypothesis. I was introduced to some work being done at the Karolinska Institute in this direction by an old student of mine, Dr Sunder. He wrote to tell me that my pet theory of learning from nature has now been taken up in the west and they also think it might yield better results. We shall discuss just one area for this write up.
     
    Chronic kidney failure (CKF) has been a very lucrative medical business for the corporate lobby next only to cardiac interventions and keeping dying patients in the ICU for the last ten days.In the US there are many “dialysis only” facilities. They are like the hair cutting shops. Patients walk in and remain there for a few hours and get dialysed and go home to come back again at periodic intervals. They might have about a dozen beds at a given time used for dialysis. Reports say that this is such a good business that these doctors do not advice their patients a kidney transplant at the right time when it could be more beneficial to the patients. Instead they wait till the last minute when transplant could be more dangerous and less useful. All this is because they want their clients for longer time with the dialysis centres in order to make more money. This is the audit report. Kidney transplant is another big business which all of us know in great detail.
     
    But look at nature. The American native bear (ursidae) is a good example here. These bears hibernate for months without any food or water. They do not pass any urine and have no exercise at all, they remain immobile for months. They sleep all the time. But when they wake up they are as fit as they were and might even attack their enemy with the same ferocity as they could do while they were ambulant. It is interesting to note that when they wake up they have very low urea nitrogen levels, healthy lean body mass, very strong bones, and no evidence of any thrombotic complications! If only our scientists could find out how and why these bears do not develop uraemia, muscle wasting, bone density loss (osteoporosis) and atherosclerosis and thrombotic complications we will have found out novel and easy methods of treating chronic kidney failure patients without dialysis and transplant as of now! 
    Million dollar question here is who will fund this “rice bowl breaking” research effort? If successful this will demolish the very lucrative dialysis and kidney transplant businesses. Please understand that neither dialysis nor kidney transplant is a cure for chronic kidney failure. They are only quick-fix solutions of modern medical science, similar to many others like them. But the industry likes these quick fixes in place of permanent cures!
     
    Contrast this with our science where we create disease models in animals, mostly rats, dogs and pigs. We try and study them to gain our present wisdom. What we do not realise is that they are in no way closer to human physiology and when we create human diseases in them they react, sometimes in a diametrically opposite direction. One example would do to explain. We produce heart failure in rats and then use our new chemical molecules on them to see if they work and if they do we use them in humans. Some years ago there was a wonder drug called, Milrinone, a cousin of amrinone. This showed wonderful results in rats in the treatment of heart failure, one of the biggest problems of old age. The company was so impressed that it convinced (lobbied) the FDA to pass it even without human studies. Indian ‘great’ cardiologists used to get the drug from USA for their rich patients, quite a lot of whom met their makers prematurely but the death was blamed on the bad heart failure. Soon enough the first human study PROMISE (Prospective randomised milrinone evaluation study) was started. Within six months into the study the preliminary report showed 37% extra unexplained deaths in the milrinone wing of the trial compared the placebo and the study was stopped and the drug withdrawn from the market. Lots of people had died by then. Later physiologic studies showed that the drug, in fact, helps a rat’s heart while it is dangerous for the failing human heart! We do not go into the details here.
     
    Respect nature as your mother and learn from her; if you abuse nature she will kick you in the teeth! Scientists! Are you listening? Long live mankind learning from nature as our Indian scientists of yore did.
     
     “In all things in nature there is something of the marvellous”—Aristotle.
     
    (Professor Dr BM Hegde, a Padma Bhushan awardee in 2010, is an MD, PhD, FRCP (London, Edinburgh, Glasgow & Dublin), FACC and FAMS. He is also Editor-in-Chief of the Journal of the Science of Healing Outcomes, chairman of the State Health Society's Expert Committee, Govt of Bihar, Patna. He is former Vice Chancellor of Manipal University at Mangalore and former professor for Cardiology of the Middlesex Hospital Medical School, University of London.)
     
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    MUTHURAJU p

    7 years ago

    This is very great message for mankind. Every human being must read the article if who read this no doubt them self become a nature Doctor Thank you Dr BM HEGDE

    Sunlight: The ‘be all and end all’ of human health

    The sun teaches two important lessons: it does not make any difference and shines on everyone, rich or poor showing us the universality of existence. The more important lesson that the sun teaches us is humility, the kingpin for good health and happiness. The sun has been burning for so long without exhausting his fuel!

    Niels Reyberg Finson was an Icelander who studied both in Iceland and Denmark. After graduation in medicine he started doing his own curious research although he tried to do many other things in addition, without much success. He was the first to treat skin tuberculosis with sunlight showing thereby the anti-germ effect of sunlight. In the year 1903, Reyberg, who was by then crippled by a killer disease, got a Nobel Prize for his work.
     

    We get our energy for running the body chemistry from the ultraviolet region of sunlight. If the sun were to go on strike we will all perish! In addition, sunlight gives us the most useful vitamin D3, which is the basis of our immune system health and bone health. Animals which have their back to the sun all the time do not get decreased bone density. People in Europe and the northern hemisphere need more exposure to sun to remain healthy, especially in winter. They cannot tolerate very hot sun as they have melanin deficiency in their skin compared to us in the tropics. If they migrate to the tropics, after a few generations, their progeny also would be dark skinned like us and vice versa.
     

    However, the drug and cosmetic industry funded research has created a myth that sunlight is bad for the skin and might produce skin cancers, etc. If that were true most of us and all Africans should be full of skin cancers. They sell billions of dollars’ worth skin care products—most of which contain dangerous carcinogenic chemicals. Independent research has proven that the skin cancer increase in incidence is basically due to these chemicals and not the sun.
     

    Bio-mimicry is the new name for learning science from nature. Nature does not do any activity that is destructive to humans and other inhabitants of the planet. Sunlight, by no stretch of imagination, can be bad for us. Too much of anything is bad anyway. Lot of our elderly folk would do well to expose themselves to good sunlight to keep their health in good shape and specially their bone health. The need for taking artificial vitamin D3 and the dangerous calcium salts could all be stopped if we expose ourselves to sun without any cream. Even dark glasses might not be good for the eyes as our pineal gland and the pituitary gland get their stimulus from the sunlight entering the eyes!
     

    Incidentally oral calcium supplements have come under great research and now we know that calcium does lot of damage to the health. Firstly, calcium intake as a chemical only increases the calcium loss in the urine—so called calcium induced calcium loss. At the end of the day one might end up with negative calcium balance. In addition calcium intake has been shown to increase vessel wall calcium deposits worsening atherosclerosis. But the calcium deposits in the heart vessels might stimulate heart attacks also!
     

    Now comes another study from Edinburgh University where scientists observed that sunlight stimulates human cells to increase the production of nitric oxide, the best elixir for vessel health. Nitric oxide is the stuff that keeps our blood vessels relaxed and open thus lowering blood pressure and increasing blood flow to all organs. The ultraviolet light in the sun's rays stimulate the nitric oxide synthase in the cell cytoplasm which in turn switches on the production of more nitric oxide (NO), the health giving endothelium relaxing factor (EDRF).
     

    The same rays also stimulate two other vital enzymes in the cell cytoplasm—HSP 70 and VEGF synthase. The first one, otherwise called the stress relaxing protein (SRP) helps many body functions while VEGF protein encourages neo-vascularisation, new vessel forming for collateral circulation, very good for the heart. All in all sunlight is the best tonic that you can get for free! It beats all the pharma giants in its protean actions in the body from germ killing to cell stimulation and supplying bone density promoter vitamin D3.
     

    Philosophically the sun teaches a very good health giving lesson to mankind. Now we know that the mind runs the body, the health of the mind is vital to our health. Negative thoughts are the killers, jokingly put—it is NOT what you eat that kills; it is what eats you that kills you. Among the negative thoughts the worst killers are hatred, greed, jealousy, anger and pride. The sun teaches two important lessons: sun does not make any difference and shines on everyone, rich or poor showing us the universality of existence. The more important lesson that the sun teaches us is humility, the kingpin for good health and happiness. The sun looks very big as he emerges on the eastern horizon but as he goes up he becomes smaller and smaller thereby telling mankind that the higher you rise in life, the humbler you become. I think this is the best advice that one could give for keeping good health. When we become truly humble, according to Indian traditions humility if the highest education, we get rid of all negative thoughts, the true causes of illness and pain.
     

    Sun is the be all and end all of all existence. The sun has been burning for so long without exhausting his fuel!
     

    (Professor Dr BM Hegde, a Padma Bhushan awardee in 2010, is an MD, PhD, FRCP (London, Edinburgh, Glasgow & Dublin), FACC and FAMS. He is also Editor-in-Chief of the Journal of the Science of Healing Outcomes, chairman of the State Health Society's Expert Committee, Govt of Bihar, Patna. He is former Vice Chancellor of Manipal University at Mangalore and former professor for Cardiology of the Middlesex Hospital Medical School, University of London.)

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    COMMENTS

    MUTHURAJU p

    7 years ago

    Thank you Dr.BM HEGDE
    This is eye opening article

    pinakin mamtora

    7 years ago

    Dear Dr.Hegde,
    Truly 'enlightening'...but, i have a practical query. Ideally, sunrays of what time of the day are relatively better for the body? I walk in the Sun from 7.30 am to 8 am almost daily. Is that okay or should I change the timing? If so, which time is advisable for sun-exposure? Thanks.

    hasmukh

    7 years ago

    Very nice and informative article. It is a pity thatPharma companies, with an eye only in their profits, misguided the whole community and made them scared of the sun and sunlight.

    srinivasan M

    7 years ago

    Thanks to the Dr. to take a subject largely ignored and reveal some startling truths about Sun rays' and effects on skin, body and mind. Also exposing very important truth about skin care products containing carcinogens. This article needs to be read and re-read to erase the memory of wonderful skin care lotions advertised on a daily basis.

    Suiketu Shah

    7 years ago

    Excellent article and 100% correct on sunlight.

    nagesh kini

    7 years ago

    Though we are blessed with more than abundant sunlight a hell of a lot of our people still suffer from Vitamin D deficiency.
    The simplest remedy is to work bare back in the garden exposing the back to the morning sun!
    It costs no money.
    Yet our folks are prescribed ad swallow costly tablets manufactured by MNCs.
    Their effects are excreted though the urine.

    B V KRISHNAN

    7 years ago

    Even now doctors continue to prescribe calcium tablets. How come the basic lesson that oral calcium has negative impact on the body is not taught to these doctors?

    REPLY

    nagesh kini

    In Reply to B V KRISHNAN 7 years ago

    If not how can the doctors and pharma cos. make money?

    nagesh kini

    In Reply to B V KRISHNAN 7 years ago

    If not how can the doctors and pharma cos. make money?

    raj

    7 years ago

    that's a really good and informative article.

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