Intermittent Fasting Could Help Prevent Type-2 Diabetes
Intermittent fasting, which means not eating during certain predetermined time slots in a day, has become more than just a dieting trend with numerous studies claiming it to be beneficial for prevention of obesity. Now, a new study has revealed that it could also act as a protective barrier against the development of type-2 diabetes. 
 
These findings come from a study, conducted by researchers from the German Institute of Human Nutrition (DIfE), published in the journal Metabolism. The results indicate that intermittent fasting improves sensitivity to the blood glucose-lowering hormone insulin and protects against fatty liver. 
 
Fatty liver has been thoroughly investigated as a known and frequently occurring disease; but little is known about the excess weight induced fat accumulation in the pancreas and its effects on the onset of type-2 diabetes. The team, led by Prof Annette Schürmann and Prof Tim J Schulz of DIfE, has found that overweight mice prone to diabetes have a high accumulation of fat cells in the pancreas. They realised that mice resistant to diabetes due to their genetic make-up, despite excess weight, had hardly any fat in the pancreas; instead, they had fat deposits in the liver. 
 
“Fat accumulations outside the fat tissue, for example in the liver, muscles or even bones, have a negative effect on these organs and the entire body. What impact fat cells have within the pancreas has not been clear until now,” said Prof Schürmann, head of the department of experimental diabetology at DIfE and speaker of the German Center for Diabetes Research (DZD). 
 
For the study, the research team divided the overweight animals, which were prone to diabetes, into two groups. One group was allowed to eat without any restrictions, i.e., as much as they wanted, whenever they wanted. The other group underwent an intermittent fasting regimen—one day, the rodents received unlimited chow; but the next day, they were not fed at all. After a period of five weeks, the researchers observed differences in the pancreas of the mice with fat cells being accumulated in the group who had no restrictions placed on food consumption. Conversely, animals in the other group had hardly any fat deposits in the pancreas.
 
“Under certain genetic conditions, the accumulation of fat in the pancreas may play a decisive role in the development of type-2 diabetes,” said Prof Schulz, head of the department of adipocyte development and nutrition at the Research Centre.
 
The collated data from this study does seem promising as it presents an alternate way to reduce liver fat and, consequently, prevent type-2 diabetes. Intermittent fasting could be a promising therapeutic approach in the future. The added advantage is that it is non-invasive, easy to integrate into everyday life and does not require drugs. But it is important to realise that this alone may not be enough to prevent the disease. 
 
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    COMMENTS

    RUSHIKESH YOGENDRA DHEBAR

    2 months ago

    Dear Akshay marvelous article which provides us day to day how to eat and ignore food in our life. Since long doctors advised to take intake in fracture timing 3/4 time in day. I have experience in two days straching eating and feel better one. Moreover you r requested to more research article on captions subject. God bless you

    Modern Foods Are Too Sweet, Reveals Study
    A comprehensive analysis of reviews by Amazon customers has revealed that modern food products are too sweet. This conclusion comes from a study that analysed food product reviews published on Amazon, over the course of a decade. 
     
    The study was conducted by researchers from the Monell Chemical Senses Center, who used a ‘sophisticated statistical modelling program’ to find words which relate to a variety of aspects pertaining to food products, such as taste, texture, odour, spiciness, cost, health and customer service. After collating, and sifting through the data, complaints about excessive sweetness within the reviews seemed to eclipse all others. Results of the study have been published in the scientific journal Physiology & Behaviour.
     
    “This is the first study of this scale to study food choice beyond the artificial constraints of the laboratory,” said lead author Dr Danielle Reed, a behavioural geneticist at Monell. Researchers looked at 383,568 food reviews published about 67,553 products, by 256,043 Amazon customers, over a 10-year period. With the assistance of machine learning algorithms, researchers were able to go through this vast archive and make determinations about the food, eventually realising that the majority of complaints were about how much sugar or other sweeteners were used in these items. “Sweet was the most frequently mentioned taste quality and the reviewers definitively told us that human food is over-sweetened,” said Dr Reed.
     
    “Reading and synthesizing almost 400,000 reviews would essentially be impossible for a human team, but recent developments in machine learning gave us the ability to understand both -- which words are present and also their underlying semantic meaning,” added study co-author Dr Joel Mainland, an olfactory neurobiologist at Monell.  
     
    The study found that the ‘too sweet’ complaint impacted nearly 1% of all food product reviews, with excessive sweetness being mentioned 25 times more than complaints about too little sweetness. Furthermore, 11% of the reviews described how sweet a particular product tasted, almost three times more than bitterness. Surprisingly, saltiness was rarely mentioned, even when there has been a lot of public health concern about excess salt consumption.
     
    To better understand individual differences in how people respond to a particular food, researchers looked at responses to 10 particular products that received the widest range of ratings - defined by the variability in the number of stars the product received. The analysis revealed that the two main factors that tended to account for polarising reviews for a product were: product reformulation and differing perspectives on the product’s taste. They found that people often rated the sweetness of a product differently. Response to a product’s smell also contributed to differences in opinion about a particular product. 
     
    “Genetic difference in taste or olfactory receptor sensitivity may help account for the extreme reactions that some products get and looking at the responses to polarizing foods could be a way to increase understanding of the biology of personal differences in food choice,” explained Dr Reed. 
     
    Overall, these results support the importance of taste in real world food ratings and individualised taste experiences, such as whether a product is ‘too sweet’. Researchers are confident that analysis of consumer review datasets is a promising methodology for the emerging field of sensory nutrition, as it can provide information about purchasing decisions and customer sensory responses to commercially available products.
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    Weight Loss, Muscle Building, Sports Performance or Energy Supplements Linked to ‘Severe Medical Outcomes’
    According to a new research led by Harvard’s TH Chan School of Public Health, consumption of dietary supplements, peddled for weight loss, muscle building and energy, may be linked to linked to nearly three times as many severe medical outcomes in children and young adults, compared to consumption of vitamins. 
     
    The study was published online on 5 June  2019 in the Journal of Adolescent Health
     
    In the US, Food and Drugs Administration (USFDA) has issued innumerable warnings about supplements aimed at weight loss, muscle building or sport performance, sexual function and energy, which are used by young people. The study was led by Flora Or, a researcher with Harvard Chan School's ‘strategic training initiative for the prevention of eating disorders’.
     
    The data was drawn from adverse event reports between January 2004 and April 2015 in FDA’s adverse event reporting system on the food and dietary supplements database. The researchers analysed the risk for severe medical events which were defined as death, disability and hospitalisation in individuals aged 0 and 25 years.
     
    The researchers found that there were 977 single-supplement-related adverse event reports for the target age group. Of those, approximately 40% involved death and hospitalisation. Offending supplements were associated with almost three times the risk for severe medical outcomes compared to those consuming vitamins. Among the worst were supplements sold for sexual function and colon-cleanse which were associated with approximately two times the risk for severe medical outcomes compared to vitamins.
     
    Many of these supplements were found to be adulterated with prescription pharmaceuticals, banned substances, heavy metals, pesticides and other dangerous chemicals. Earlier, other studies have linked weight loss and muscle building supplements with stroke, testicular cancer, liver damage and even death.
     
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    COMMENTS

    NARESH GAJRIA

    2 months ago

    Names and Brands have not been specified. Is adulteration the main concern or the content?

    tanay

    3 months ago

    Any muscle building supplement isha waste of money....you can build good muscle by eating natural high protein food and progressive resistance training

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