Corona Virus (COVID-19) Latest Updates
India has over 60 lakh Covid cases
28-09-2020 10.10

With a spike of 82,170 coronavirus cases and 1,039 deaths in 24 hours, India's tally on Monday breached the 60 lakh-mark with a total of 60,74,702 cases.

Out of these, 9,62,640 are currently active; 50,16,520 have been discharged, while 95,542 lost the battle against the viral disease.

On July 17, India had logged 10 lakh cases, which then doubled to 20 lakh on August 7. The country added another 10 lakh on August 23 and went past 40 lakh on September 5. In 11 days, it added another 10 lakh cases, mounting to 50 lakh cases. Twelve days later the tally has mounted to 60 lakh.

While the recovery rate stands at 82.58 per cent, one of the highest in the world; the fatality rate has come down to 1.57 per cent, the data from the Ministry of Health and Family Welfare said.

Maharashtra continues to be the worst-hit with a total of 13,39,232 cases including 35,571 deaths; followed by Andhra Pradesh, Tamil Nadu and Karnataka.

According to the data from the Indian Council of Medical Research (ICMR), 7,09,394 sample tests were conducted across the country in a single day on Sunday, taking the total number of samples tested so far to 7,19,67,230.

On the global front, India rallies behind the US, which has recorded 71,13,666 cases and 2,04,750 deaths. As of Monday morning, the total number of cases in the world stood at 3,29,77,556 and the fatalities rose to 9,96,674.

 
 
With 85,362 new cases, India's corona tally reaches 59 lakh
26-09-2020 10:30

With a spike of 85,362 coronavirus cases and 1,089 deaths in 24 hours, India's tally on Saturday reached 59,03,932 cases, the Ministry of Health and Family Welfare said.

Out of the total cases, 9,60,969 are currently active, 48,49,584 have been discharged, while 93,379 lost the battle against the viral disease.

While the recovery rate stands at 81.74 per cent, the fatality rate has come down to 1.59 per cent.

Maharashtra continues to be the worst-hit with a total of 13,00,757 cases, including 34,761 deaths; followed by Andhra Pradesh, Tamil Nadu and Karnataka. About 75 per cent of the new cases are found to be concentrated in ten states and UTs.

According to the data from the Indian Council of Medical Research (ICMR), India conducted 14,41,535 sample tests in a single day on Friday, taking the total number of samples tested so far to 7,02,69,975.

On the global front, India rallies behind the US, which has recorded 70,32,524 cases and 2,03,657 deaths. As of Saturday morning, the total number of cases in the world stood at 3,24,71,119 and the fatalities rose to 9,87,593.

 
 
India reports 86,052 new Covid cases; Total crosses 58 lakh
25-09-2020 11:30

India has reported 86,052 new Covid-19 cases and 1,141 deaths in the last 24 hours taking its tally to 58,18,570, the Ministry of Health and Family Welfare said on Friday.

Mizoram is the only state that has not reported any deaths, the ministry data showed and pointed out that more than 70 per cent of the 92,290 deaths so far are due to comorbidities.

Maharashtra is the worst affected state. It has reported 459 deaths in the past 24 hours. Total death tally in the state is 34,345 so far. There are 2,75,404 active Covid cases and so far, a total 9,73,214 people have recovered in the state. In the last 24 hours, 17,184 left quarantine centres and hospitals after recuperating completely.

Karnataka has reported 65 deaths in the last 24 hours taking its toll to 8,331. There are 95,568 active Covid cases in the state. In the past one day, 6,748 recovered of the total 4,44,658 recoveries in the state.

Ladakh where the country is facing tension at the borders with China reported three deaths from Covid in the last 24 hours. A total of 54 people have succumbed to the deadly virus in the newly created union territory. There are 1,022 active Covid cases. So far 2,893 people have recovered from the deadly virus in Ladkah and in the last 24 hours a total 49 people have left hospitals and quarantine centres.

A senior officer in the ministry stated that a total 81,177 people were discharged from various hospitals and quarantine centres in the last 24 hours across the country. So far, a total 47,56,164 people have recovered from the deadly viral infection.

The recovery rate from coronavirus in India at 81.74 per cent is the highest in the world. There are 9,70,116 active cases presently in the country.

According to the Indian Council of Medical Research, a total 14,92,409 people in India were tested for Covid on Thursday. The institute stated that the cumulative total samples tested so far stands at 6,89,28,440.

 
 
Over 57 lakh Covid cases, above 91,000 deaths in India
24-09-2020 10:30

With a spike of 86,508 coronavirus cases in 24 hours India's tally on Thursday reached 57,32,518 and there were 1,129 deaths in one day.

Out of the total cases, 9,66,382 are currently active, 46,74,987 have been discharged, while 91,149 lost the battle against the viral disease.

Continuing with its record, India posted 81.55 per cent of recoveries while the fatality rate stood at 1.59 per cent, the data from the Ministry of Health and Family Welfare said.

Maharashtra continued to be the worst-hit with a total of 12,63,799 cases, including 33,886 deaths; followed by Andhra Pradesh, Tamil Nadu, Karnataka and Uttar Pradesh.

According to the data from the Indian Council of Medical Research (ICMR), India conducted 11,56,569 sample tests in a single day on Wednesday, taking the total number of samples tested so far to 6,74,36,031.

 
 
India with over 56 lakh Covid cases, goes past 90,000 deaths
23-09-2020 10:30

India's tally on Wednesday crossed 56 lakh cases following a spike of 83,347 fresh coronavirus infections reported in 24 hours, according to data from the Ministry of Health and Family Welfare.

There were 1,085 new deaths as the toll in past more than eight months reached 90,020 and the total cases mounted to 56,46,010.

India is the second worst hit country by the pandemic just behind the US, where they have recorded 2 lakh deaths.

Out of the total cases in India, 9,68,377 are currently active, and 45,87,613 have been discharged, making the rate of recoveries best in the world.

While the recovery rate stands at 81.25 per cent, the fatality rate has come down to 1.59 per cent.

Maharashtra continues to be the worst-hit with a total of 12,42,770 cases, including 33,407 deaths, followed by Andhra Pradesh, Tamil Nadu, Karnataka and Uttar Pradesh.

According to the data from the Indian Council of Medical Research (ICMR), India conducted 9,53,683 sample tests in a single day on Tuesday, taking the total number of samples tested so far to 6,62,79,462.

The Union Health Ministry had said that it has increased the testing infrastructure exponentially. Till July 7, India had tested 1 crore samples and it took us 27 days to add 2 crore tests. By August 3, we had tested 3 crore samples. During this period, the laboratories were increased from 1,100 to 1,300 in the country.

On Tuesday, the Indian Council of Medical Research (ICMR) said that the efficacy of the Covid-19 vaccinein India might not reach 100 per cent. "We are aiming for 100 per cent efficacy but may land between 50 to 100 per cent. However, it still would be an effective vaccine against the virus," Balram Bhargava, ICMR Director General said.

 
 
Across 55 lakh, India's active cases dip, recoveries shoot up
22-09-2020 10:50

In a major relief India showed a spike of 75,083 fresh coronavirus cases in a day, nearly 20,000 less than its daily surge reported last week. Even though it crossed the 55 lakh-mark of total cases, it continued to show highest recovery rate, Health Ministry data showed on Tuesday.

There were now 9,75,861 active cases, while 44,97,867 have recovered, with 1,01,468 in the past 24 hours while 1,053 died taking the toll to 88,935.

With a tally of 55,62,663 cases, India's recovery rate stands at 80.86 per cent, and the fatality rate is 1.60 per cent, according to the Ministry of Health and Family Welfare data.

Even though India rallies behind the US for the total number of coronavirus cases, it has overtaken the country to become number one in terms of global recoveries.

Maharashtra continues to be the worst-hit with a total of 12,24,380 cases including 33,015 deaths; followed by Andhra Pradesh, Tamil Nadu, Karnataka and Uttar Pradesh.

According to the data from the Indian Council of Medical Research (ICMR), India conducted 9,33,185 sample tests in a single day on Monday, taking the total number of samples tested so far to 6,53,25,779.
 
 
India records 86,961 Covid cases and 1,130 deaths in past 24 hours
21-09-2020 10:50

With 86,961 fresh coronavirus cases and 1,130 deaths in 24 hours, India's Covid-19 tally on Monday inched closer to 55 lakh-mark with a total of 54,87,580 cases in 235 days since the first case was reported on January 30.

Out of the total cases, 10,03,299 are currently active, 43,96,399 have recovered, while 87,882 lost the battle against the pandemic.

Even though India rallies behind the US for the number of coronavirus cases, it has overtaken the country to become number one in terms of recoveries. The recovery rate stands at 79.68 per cent, while the fatality rate is 1.61 per cent, the data from the Ministry of Health and Family Welfare said.

Maharashtra continues to be the worst-hit with a total of 12,08,642 cases, including 32,671 deaths; followed by Andhra Pradesh, Tamil Nadu, Karnataka and Uttar Pradesh.

According to the data from the Indian Council of Medical Research (ICMR), India conducted 7,31,534 sample tests in a single day on Sunday, taking the total number of samples tested so far to 64,392,594.

India is the second worst-hit behind the US which has 67,99,044 cases and 1,99,474 deaths. The total number of cases in the world stands at 3,09,18,269 and the fatalities are 9,59,332.

The other top 15 countries with the maximum amount of cases are Brazil (45,44,629), Russia (10,98,958), Peru (7,62,865), Colombia (7,58,398), Mexico (6,97,663), South Africa (6,61,211), Spain (6,40,040), Argentina (6,31,365), France (4,67,614), Chile (4,46,274), Iran (4,22,140), the UK (3,96,744), Bangladesh (3,48,918), Saudi Arabia (3,29,754) and Iraq (3,19,035), the CSSE figures showed.

 
 
Over 96,000 Covid cases in India over past 24 hours
18-09-2020 10:20

With a massive spike of 96,424 new cases and 1,172 deaths in the last 24 hours, India's Covid-19 tally on Friday crossed the 52-lakh mark.

Out of the total 52,14,677 cases, 10,17,754 are active while 41,12,551 have recovered from the deadly virus and 84,372 succumbed to the disease, the data released by the Ministry of Health and Family Welfare showed.

Maharashtra remains the worst hit state followed by Karnataka, Uttar Pradesh, Andhra Pradesh and Delhi.

According to the data released by the MoHFW, the fatality rate has reached to 1.63 per cent while the recovery rate is at 78.64 per cent.

As per the Indian Council of Medical Research (ICMR), 6,15,72,343 samples were tested up to September 17 of which 10,06,615 were tested in the past 24 hours.
 
India's Covid-19 cases cross 50 lakh-mark
16-09-2020 10:00

With a massive spike of 90,123 cases, including 1,290 deaths in 24 hours, India's tally on Wednesday crossed the grim mark of 50 lakh, according to the Ministry of Health and Family Welfare.

The total corona tally stands at 50,20,359 cases.

On July 17, India had logged 10 lakh cases, which then doubled to 20 lakh in 20 days on August 7. The country added another 10 lakh on August 23 and went past 40 lakh on September 5. In 11 days, it added another 10 lakh cases, mounting to 50 lakh cases on Wednesday.

Out of the total cases, 9,95,933 are active, 39,42,360 have been discharged, while 82,066 lost the battle against the viral disease. In the last 24 hours, 82,961 patients were discharged.

While the recovery rate stands at a whooping high of 78.53 per cent, the fatality rate has come down to 1.63 per cent, the data from the Ministry of Health and Family Welfare said.

Maharashtra continues to be the worst-hit with a total of 10,97,856 cases, including 30,409 deaths; followed by Andhra Pradesh, Tamil Nadu, Karnataka and Uttar Pradesh.

On Monday, the ministry asked Delhi, Maharashtra, Andhra Pradesh, Karnataka, and Tamil Nadu to ramp up their testing. These are the states whose positivity rates are faring above the national average. Meanwhile, four of these states account for more than half (53.5 per cent) of the active cases.

According to the data from the Indian Council of Medical Research (ICMR), India conducted 11,16,842 sample tests in a single day on Tuesday, taking the total number of samples tested so far to 5,94,29,115.
 
 
Over 80,000 people have lost Covid battle so far in India as tally breaches 49 lakh mark
15-09-2020 10:30

India has lost 80,776 people to the Coronavirus till date, Health Ministry data revealed on Tuesday that also showed a spike of 83,809 new cases in the past 24 hours.

With 1,054 deaths India now has a toll that is barely 5,000 short of total Covid-19 cases reported in China, the ground zero of the virus that turned into a pandemic since the first case was reported in Wuhan in December 2019.

China has so far recorded only 85,202 cases while India that reported its first Covid-19 case on January 30, now has 49,30,236 cases, according to the Ministry of Health and Family Welfare data.

Out of the total cases, 9,90,061 are the active, 38,59,399 have been discharged, while 79,292 were cured in the past one day.

While the recovery rate is 78 per cent, the fatality rate is 1.64 per cent.

On July 17, India had logged 10 lakh cases, which then doubled to 20 lakh in 20 days, on August 7. The country added another 10 lakh on August 23 and went past 40 lakh on September 5.

Maharashtra continues to be the worst-hit state with a total of 10,60,308 cases, including 29,531 deaths; followed by Andhra Pradesh, Tamil Nadu, Karnataka and Uttar Pradesh.

According to the data from the Indian Council of Medical Research (ICMR), India conducted 10,72,845 sample tests in a single day on Monday, taking the total number of samples tested so far to 5,83,12,273.

The US is the only nation worse hit than India with 65,53,303 cases and and 1,94,489 deaths so far.
 
India records 92,000 new cases, Covid tally crosses 48 lakh
14-09-2020 10:50

With a massive spike of 92,071 cases, including 1,136 deaths in 24 hours, India's total tally of Covid-19 cases reached 48,46,427, according to the Ministry of Health and Family Welfare data on Monday.

Out of the total cases, 9,86,598 are the active ones, 37,80,107 have been discharged, while 79,722 lost the battle against the viral disease. In the last 24 hours, 77,512 patients were discharged.

While the recovery rate is 77.88 per cent, the fatality rate is 1.65 per cent, the data from the Ministry of Health and Family Welfare said.

On July 17, India had logged 10 lakh cases, which then doubled to 20 lakh in 20 days, on August 7. The country added another 10 lakh on August 23 and went past 40 lakh on September 5.

Maharashtra continues to be the worst-hit state with a total of 10,37,765 cases, including 29,115 deaths; followed by Andhra Pradesh, Tamil Nadu, Karnataka and Uttar Pradesh.

According to the data from the Indian Council of Medical Research (ICMR), India conducted 9,78,500 sample tests in a single day on Sunday, taking the total number of samples tested so far to 5,72,39,428.

On the global front, India remains the second worst-hit nation with the Covid-19 pandemic while the US leads the board with 65,19,121 total cases and 1,94,041 deaths. The maximum number of deaths occurred in the US followed by Brazil and India.

Meanwhile, on Sunday, the Ministry of Health and Family Welfare asked Maharashtra, Andhra Pradesh, Karnataka, Telangana, Gujarat, Rajasthan and Madhya Pradesh to make adequate oxygen availability while ensuring unrestricted intra as well as interstate movement of the oxygen.

To allay fears regarding the safety aspect of the coronavirus vaccines, the Union Health Minister Harsh Vardhan said that he will be happy to take the first dose. He assured the vaccine will be first made available to those who need it the most, irrespective of their paying capacity.

 
 
With 97,570 new cases India's single day surge is highest
12-09-2020 10:10

India on Saturday once again recorded an unprecedented spike in a single day as 97,570 fresh Covid cases were recorded taking the total tally to 46,59,984, the Union Health Ministry data revealed.

It is more than double the single day spike in the US, which is the only country ahead of India.

There were 1,201 deaths reported in the past 24 hours, with the toll reaching 77,472 so far.

Out of the total cases, 9,58,316 are active, 36,24,196 have recovered so far. The first case was reported in the US on January 21, while in India it was on January 30. The US accounts for the world's highest number of cases and deaths at 64,43,048 and 1,92,968 respectively, according to the CSSE.

India has long breached US' single day tally of cases, but the US still holds the single day deaths record of 2,494 on April 15.

Maharashtra, Andhra Pradesh, Tamil Nadu, Karnataka, and Uttar Pradesh are the worst-hit states. They account for above 60 per cent of the active cases, according to the Ministry.

The recovery rate stands at 77.65 per cent, while the fatality rate is 1.67 per cent, the Ministry data showed.

According to the data from the Indian Council of Medical Research (ICMR), India conducted a record 10,91,251 tests in a single day on Friday, taking the total number of samples tested so far to 5,51,89,226.

 
 
Unprecedented surge in single-day spike of Covid cases, deaths in India
11-09-2020 10:10

India on Friday recorded an unprecedented rise in single-day spike both in number of fresh cases and deaths in 24 hours. There were 96,551 new infections reported that took the total tally to 45,62,414, the Union Health Ministry data revealed.

There were 1,209 deaths reported in the past 24 hours, which is also the highest fatality in a single day, with the toll reaching 76,271 so far.

Out of the total cases, 9,43,480 are active, 35,42,663 have recovered so far as India rallies just behind the US. The first case was reported in the US on January 21, while in India it was on January 30. The US accounts for the world's highest number of cases and deaths at 63,95,904 and 1,91,753, respectively.

India has breached US' single day tally of cases, but the US still holds the single day deaths record of 2,494 on April 15.

Maharashtra, Andhra Pradesh, Tamil Nadu, Karnataka, and Uttar Pradesh are the worst-hit states. They account for over more than 60 per cent of the active cases, according to the Ministry.

The recovery rate stands at 77.74 per cent, while the fatality rate has dipped to 1.68 per cent, the Ministry data showed.

According to the data from the Indian Council of Medical Research (ICMR), India conducted a record 11,63,542 tests in a single day on Thursday, taking the total number of samples tested so far to 5,40,97,975.

Meanwhile, the Health Ministry and ICMR have jointly written to all the States and UTs and urged them to ensure that the all symptomatic negative cases of rapid antigen test are mandatorily retested using the gold standard RT-PCR test to ensure that such symptomatic negative cases do not remain untested and spread the disease

The Ministry has also urged the States and UTs to urgently establish a monitoring mechanism in every district, a designated officer or a team, and at the State level to follow up such cases.

 
India now inching closer to 1 lakh cases per day
10-09-2020 10:10

India on Thursday witnessed a record spike of 95,735 new Covid-19 cases, the highest single-day increase till date, taking the total tally to 44,65,863, the Union Health Ministry data revealed.

There were 1,172 deaths reported in the past 24 hours, which is also the highest fatality in a single day so far. India on Tuesday recorded 1,133 deaths and on July 29 there were 1,129. India's deaths per day are now crossing US' which is the worst-hit by the pandemic.

India is currently the second-worst hit country after the US since the first case was reported on January 30.

Out of the total 44,65,863 cases, 9,19,018 are active, 34,71,783 have recovered so far, while 75,062 have died.

The recovery rate stands at 77.77 per cent, the fatality rate at 1.69 per cent, the Ministry data showed.

Maharashtra, Andhra Pradesh, Tamil Nadu, Karnataka, and Uttar Pradesh are the worst-hit states. They account for over 62 per cent of the active cases, according to the Ministry.

According to the data from the Indian Council of Medical Research (ICMR), India conducted a record 11,29,756 tests in a single day on Wednesday, taking the total number of samples tested so far to 5,29,34,433.

 
 
With 89,000 fresh cases India's Covid-19 tally reaches 43.7 lakh
09-09-2020 10:55

India on Wednesday witnessed a spike of 89,706 fresh cases of novel coronavirus (Covid-19) taking the total tally to 43,70,128 with 1,115 deaths due to pandemic in last 24 hours, the Union Health Ministry data revealed.

The spike of 89,706 cases comes a day after India witnessed a decline of fresh cases on Tuesday with 75,809 cases.

India now is the second worst hit country after the US, with 43.7 million Covid-19 cases since the first was reported on January 30.

Out of the total 43,70,128 cases, 8,97,394 are active cases; 33,98,844 have recovered so far while 73,890 lost the battle against the deadly virus.

While the recovery rate was at a whopping high of 77.77 per cent, the fatality rate stands at 1.69 per cent, the data from the Ministry of Health and Family Welfare shows.

Maharashtra, Andhra Pradesh, Tamil Nadu, Karnataka, and Uttar Pradesh are the worst-hit states. These five states account for over 62 per cent of the active cases, according to the Health Ministry.

According to the data from the Indian Council of Medical Research (ICMR), India conducted a record 11,54,549 tests in a single day on Tuesday, taking the total number of samples tested so far to 5,18,04,677.

 
 
With 1,133 deaths, India witnesses highest single-day toll
08-09-2020 11:55

After breaching single day records of highest Covid cases in the world going past 90,000, India on Tuesday said it has registered 75,809 fresh cases in 24 hours, when it marked the largest spike in deaths in a day with 1,133 new fatalities.

India now is the second worst hit country after the US, with 42,80,442 coronavirus cases since the first was reported on January 30. The US has recorded 63,00,431 cases and 1,89,206 deaths so far, since the virus was first detected in China's Wuhan in December 2019.

Out of the total 42,04,613 cases, 8,836,97 are active cases; 33,23,950 have recovered so far while 72,775 lost the battle against the deadly virus.

While the recovery rate was at a whopping high of 77.65 per cent, the fatality rate stands at 1.70 per cent, the data from the Ministry of Health and Family Welfare shows. The last highest deaths recorded due to the virus on a single day was on July 23, when 1,129 died in 24 hours.

Maharashtra, Andhra Pradesh, Tamil Nadu, Karnataka, and Uttar Pradesh are the worst-hit states. These five states account for over 62 per cent of the active cases, according to the Health Ministry.

According to the data from the Indian Council of Medical Research (ICMR), India conducted a record 10,98,621 tests in a single day on Monday, taking the total number of samples tested so far to 5,06,50,128.

 
 
With 83,341 new corona cases, India's tally reaches 39 lakh
04-09-2020 10:40 
 
With 83,341 fresh coronavirus infections in 24 hours, India's tally mounted to 39,36,747 on Friday, while the death toll climbed to 68,472 with 1,096 more fatalities, said the Health Ministry.
 
Out of total confirmed cases, 8,31,124 are the active cases, while a total of 30,37,151 have recovered from the virus so far. With 66,659 recoveries in a day, the recovery rate has increased to 77.15 per cent.
 
The number of patients recovering is on a steady rise over the past several months. As the daily recoveries increase, India has registered more than 60,000 recoveries each day, eighth day in a row.
 
"Less than two per cent of the active cases are on ventilators; two per cent is in ICUs; and less than 3.5 per cent are on oxygen support. This is due to early detection, early hospitalisation and effective clinical management based on the Standard Treatment Protocol," the Health Ministry said.
 
Maharashtra continues to be the worst-hit with a total of 8,43,844 cases and 25,586 deaths; followed by Andhra Pradesh with 4,65,730 cases and 4,200 deaths. Tamil Nadu, Karnataka, Uttar Pradesh, Delhi, West Bengal, and Bihar come next.
 
According to the data from the Indian Council of Medical Research (ICMR), India conducted a record 11,69,765 tests in a single day on Thursday, taking the total number of samples tested so far to 4,66,79,145.
 
On the global front, India still remains the third worst hit nation with the Covid-19 pandemic while the US and Brazil lead the board with 6,149,265 and 4,041,638 total cases, respectively. India is a lakh cases short of crossing Brazil.
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    Body Temperature, Key Factor for Benefits of Caloric Restriction
    Restricting calorie consumption has been proven to have many benefits and now a new study has revealed that body temperature plays a critical role in such diet-induced health benefits. Through their findings, the researchers are now hoping to create a medicinal compound that imitates the valuable effects of reduced body temperature. 
     
    The study has been conducted by teams from Scripps Research, led by Dr Bruno Conti and Dr Gary Siuzdak and published in the journal Science Signalling. Dr Conti has spent years studying how and why calorie restriction leads to better health, with the ultimate goal of translating his findings into medicines which could potentially mimic what occurs naturally when a person eats less. 
     
    In his previous research, he had consistently observed that when mammals consume less food, their body temperature drops accordingly. This is evolution’s way of helping mammals conserve energy until food is available again, explains Dr Conti. In humans and also other mammals, up to half of the food consumed daily is turned into energy simply to maintain core body temperature. 
     
    Dr Conti’s other research has shown that temperature reduction can cause an increased lifespan independently of calorie restriction and further that these effects involve activation of certain cellular processes most of which are yet to be identified. 
     
    Other studies also support Dr Conti’s findings and have shown that preventing a drop in body temperature can actually counteract positive effects of calorie restriction. Notably, in an experiment involving calorie-restricted mice, anti-cancer benefits were diminished when core body temperature remained the same. 
     
    The question Dr Conti addressed in the study was: "It's not easy to discern what's driving the beneficial changes of calorie restriction. Is it the reduced calories on their own, or the change in body temperature that typically happens when one consumes fewer calories? Or is it a combination of both?” Therefore, Dr Conti and his team designed an experiment that would allow them to independently evaluate the effects of reduced nutrients and those of body temperature.
     
    They set out to compare a group of calorie-restricted mice housed at room temperature - about 22°C—to another group housed at 30°C. The warmer environment was set up to invoke ‘thermo-neutrality’, a state at which most animals cannot easily reduce their body temperature. 
     
    Using a new technology called activity metabolomics, Dr Siuzdak’s team then evaluated the mice by measuring their metabolites, or chemicals released by the animals’ metabolism. Using this process, the team was able to look for the molecules in the bloodstream and in the brain that are changed by the reduction of either nutrients or body temperature. 
     
    "The data we collected showed that temperature has an equal or greater effect than nutrients on metabolism during calorie restriction," Dr Conti said. Notably, the team has been successful in the first comprehensive profiling of the metabolites that are changed by temperature reduction.
     
    Analysing the results from both groups of mice, the scientists were able to prioritise which metabolites were most responsible for triggering changes to core body temperature. In a separate experiment, they were also able to show that it is possible to administer certain metabolites as a drug to affect body temperature.
     
    Dr Conti believes that further work to validate the changes induced by temperature during calorie restriction should provide novel targets for future medicines. He calls such medicines ‘temperature mimetics’ which he hopes will offer health-promoting effects without having to reduce body temperature. 
     
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    Vitamin C Consumption, Key to Maintaining Muscle Mass in Old Age
    A new study from the University of East Anglia (UEA) has revealed that older people who consume more foods that are rich with vitamin C have the best skeletal muscle mass.
     
    Generally, as we get older, our muscle mass, strength and power to move, gradually declines, often leading to condition called sarcopenia. "People over 50 lose up to one per cent of their skeletal muscle mass each year, and this loss is thought to affect more than 50 million people worldwide. It's a big problem, because it can lead to frailty and other poor outcomes such as sarcopenia, physical disability, type-2 diabetes, reduced quality of life and death,” said lead researcher Prof Ailsa Welch, from UEA's Norwich Medical School.
     
    Currently, there are limited solutions for treating sarcopenia, so early intervention, before symptoms become too severe, is preferable. Most research, until now, has focused on the effect of increasing protein intake to prevent or treat sarcopenia. 
     
    However, this new study, published in The Journal of Nutrition, attempted to investigate the importance of dietary vitamin with loss of skeletal muscle mass and function in middle and older age. The study concluded that the more dietary vitamin C middle-aged and older adults consume, the greater their skeletal muscle mass appears to be. 
     
    Vitamin C is abundantly found in citrus fruits, berries and vegetables and people who do not consume enough of these in their diet are at risk of vitamin C deficiency which, in turn, causes weakness, tiredness and fragile bones. In extreme cases, vitamin C deficiency may lead to scurvy. 
     
    Around two-thirds of our body’s total vitamin C is found in skeletal muscle and is used for making carnitine, a substance crucial in providing energy for muscles to function, and collagen which is an essential structural component of muscle. Vitamin C is also a strong antioxidant that can help to counteract free radical molecules which increase with age. Unopposed, these free radical molecules can contribute to destruction of muscle cells. 
     
    For this study, researchers looked at data from over 13,000 men and women aged 42-82 years who were participants in the European Prospective Investigation into Cancer and Nutrition (EPIC) Norfolk study. They used biological impedance analysis, which sends small electrical signals through the body to calculate water and fat percentage, thus estimating the proportion of skeletal muscle in the body. 
     
    Participants were requested to maintain a diary of everything they ate and drank over a period of seven days so that the research team could accurately calculate their intake of dietary vitamin C. Vitamin C levels were also measured directly in their blood, providing results less susceptible to potential error in reporting diet. Participants were then grouped according to their intake of vitamin C, ranging from low to high.
     
    Analysis of the collated data took into consideration other important factors, including participant’s physical activity, protein and energy intake, which might also have effects on skeletal muscle mass. 
     
    They found that participants who had consumed the highest amount of vitamin C in their diet had the greatest muscle mass. The results indicated the largest difference in women who had consumed highest category of vitamin C, showing muscle mass 3% higher than those in the lowest category. For participants under as well as over 65, vitamin C was seen to be an important factor in maintaining better skeletal mass. These findings were also supported by the fact that those with sufficient levels of vitamin C in their blood had greater muscle mass than those in the insufficient category. 
     
    "We found that nearly 60 per cent of men and 50 per cent of women participants were not consuming as much Vitamin C as they should, according to the European Food Safety Agency recommendations. We're not talking about people needing mega-doses. Eating a citrus fruit, such as an orange, each day and having a vegetable side to a meal will be sufficient for most people,” said Dr Richard Hayhoe, from UEA's Norwich Medical School.
     
    The results from this study build on the concept that optimal nutrition may help reduce the decline in muscle. This provides further emphasis and encouragement for people of all ages to follow the healthy eating guidelines and consume a wider variety of fruits and vegetables every day. 
     
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