Leisure, Lifestyle & Wellness
Traditional cholesterol testing may not predict heart disease
Traditional testing for the level of a specific component of high-density lipoprotein cholesterol (HDL-C) -- the "good cholesterol" -- may not be a better predictor of the damage or disease in the heart's major blood vessels, says a study.
 
Failure of drug trials to observe benefits by elevating high-density lipoprotein cholesterol (HDL-C) in the blood has raised serious doubts about HDL-C's properties of reducing the formation of plaques that block our blood vessels and cause coronary heart disease, the researchers said.
 
Coronary artery disease (CAD) is a condition which affects the arteries that supply the heart with blood. 
 
The findings after adjusting for age, use of statins, smoking, and other factors, showed that small, dense, protein-rich particles making up "good cholesterol" may be more protective of our blood vessels than large, buoyant cholesterol-rich particles.
 
The more small and medium "good cholesterol" particles were found in the blood vessels, the less was the arterial calcification present. 
 
There was no association between large HDL- particles and coronary artery calcification.
 
The association with HDL- cholesterol was weaker and inconsistent between men and women.
 
"Our findings indicate that HDL- particles and medium-sized HDL particles are better independent markers of coronary artery disease, as reflected by coronary artery calcification, than HDL-cholesterol," said Chobufo Ditah from Hebrew University in Jerusalem, Israel.
 
"The study support previous reports suggesting that small dense HDL particles are protectively associated with risk of coronary heart disease," Ditah added.
 
For the study, published in the journal Atherosclerosis, the team recruited 274 Arabs and 230 Jews residing in Jerusalem. 
 
The team used Nuclear Magnetic Resonance (NMR) spectroscopy to identify the numbers and sizes of plasma HDL particles, and helical CT-scanning to identify calcification in their coronary arteries, reflecting the overall burden of coronary atherosclerosis. 
 
With these data in hand, they looked for associations between the concentrations and sizes of different HDL particles, and coronary artery calcification. 
 
"Based on the accumulating evidence, incorporation of medium-sized HDL particles or HDL- particles into the routine prediction of coronary heart disease risk should be considered," noted Jeremy Kark,Professor at the Hebrew University.
 
Disclaimer: Information, facts or opinions expressed in this news article are presented as sourced from IANS and do not reflect views of Moneylife and hence Moneylife is not responsible or liable for the same. As a source and news provider, IANS is responsible for accuracy, completeness, suitability and validity of any information in this article.

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COMMENTS

Ramesh Poapt

4 months ago

excellent, may Dr Hegde simplify it for its easy/simple/effective
monitoring pl.?

Hyundai to increase prices across models
Automobile manufacturer Hyundai Motor India (HMIL) on Friday said that it will increase the prices of all models across its entire range from August 16.
 
The company pointed out that the depreciation in rupee's value and increase in input cost mandated the move. 
 
"The rupee depreciation and increase in raw materials cost have impacted our overall costs," said Rakesh Srivastava, Senior Vice President, Sales and Marketing, HMIL.
 
According to Srivastava, the prices will be increased from Rs 3,000 to Rs 20,000 across models.
 
"We have been absorbing most of the costs but now we are compelled to consider the price increase. We will be increasing the prices from August 16, 2016 by Rs.3,000 to Rs.20,000 across models," Srivastava added.
 
Currently the company offers ten car models across segments -- Eon, i10, Grand i10, Elite i20, Active i20, Xcent, Verna, Creta, Elantra and Santa Fe.
 
Disclaimer: Information, facts or opinions expressed in this news article are presented as sourced from IANS and do not reflect views of Moneylife and hence Moneylife is not responsible or liable for the same. As a source and news provider, IANS is responsible for accuracy, completeness, suitability and validity of any information in this article.

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Illegal sand mining is endangering bridges, Awaaz Foundation demands full investigation
Illegal sand mining is said to have weakened the foundation of the bridge across Savitri river near Mahad, causing it to collapse, say activists. Earlier, it was reported that illegal mining of the Vaitarna river bed is endangering the railway bridge under Western Railways that is used by thousands of long distance commuters including the Rajdhani Express passengers. Callous government officials are turning a blind eye to rampant illegal sand mining, which is endangering bridges and lives of commuters. 
 
The tragic collapse of the bridge at Mahad, which had been recently certified as fit has thrown the spotlight on the incessant illegal sand mining and dredging that is rampant in the region and across the state. Sumaira Abdulali of Awaaz Foundation has written to the chief minister Devendra Fadnavis asking for a "full investigation into the possible role of sand mining leading to weakening of infrastructure such as bridges and endangering the lives of rail and road travellers”, which should include "previous occasions of bridge collapse and complaints filed by the Western Railway, Awaaz Foundation and locals at various locations".
 
In her letter Ms Abdulali writes that, "The Savitri River at Mahad is one of the many areas being misused to dredge massive quantities of sand. Sand mining sites even not directly next to the collapsed bridge, but when placed upstream and downstream of a bridge, may change the flow and increase the force of the river. Such changes could have contributed in washing away the bridge which has survived the force of nature for decades since the British era and was recently certified as safe.”
 
In 2011, a bridge at Vaitarna Creek was damaged due to sand mining at its base. The Western Railway wrote to the Government about the dangers of allowing sand mining to continue. In spite of this, a huge amount of sand continued to be extracted from the area”. Photographs take by Ms Abdulali below show that a Police chowky exists right next to the railway bridge where sand is stored in large heaps and mining continued for years directly at the base of the bridge. 
 
Major newspapers too have reported that the illegal mining of the Vaitarna river bed is endangering the railways bridge on the Western Railways that is used by thousands of long distance commuters including the Rajdhani Express. The Railways have reportedly issued a warning in 2012 with no action from the State, and a second notice has been sent on 4th June, describing bridge number 92 as being in an "endangered condition” between Saphale and Vaitarna river due to sand mining. While the railways is merely sending out notices, without stopping service and the state remains indifferent, the lives of innocent people are at risk. 
 
Ms Abdulali further writes, "Over the years, I have continued to monitor illegal sand mining sites in various coastal areas of Maharashtra. Many of these sites are in the vicinity or directly next to railway and road bridges. Sand mining in Navi Mumbai, Vaitarna Creek, Bassein Creek, Thane Creek and Savitri River all continue close to bridges and often using suction pumps.” Ms Abdulali provides photographs as recent as May 2016, of sand mining at Vaitarna creek and Mahad immediately next to road and railway bridges. Site visits since 2010 confirm that this activity has been continuous since then.
 
 
In her letter she further highlights that, “Recently, in spite of repeatedly bringing illegal sand mining to the attention of the State Government, Bombay High Court Orders and National Green Tribunal Orders to control sand mining and numerous complaints of local villagers and myself, the Maharashtra State Government has seen fit to permit sand dredging using suction pumps at some locations through a change in policy". 
 
Ms Abdulali reminded the CM that she was attacked by the sand mafia at the Tol Bridge at Mahad in the same general area as the collapsed bridge. Unbridled sand mining in the vicinity of bridges may be a major contributing cause and cannot be ruled out. Awaaz Foundation requests that such investigation takes note of the various previous occasions of bridge collapse and complaints filed by the Western Railway, and locals at various locations.
 

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COMMENTS

Deepak Narain

4 months ago

The present kind of 'free for all govt' helps only the corrupt, criminals and rich. The law and its long-drawn procedures are so framed that justice is seldom done and is very long- drawn. It suits our politicians well. They take care of each other. Mr Modi finds it very convenient for his short-term objectives. Rapes and crimes can be stopped within a month if the powerful mean business. I can do that. Only sincerity is needed. This is a golden opportunity for the BJP govt and is being frittered away. Hinduism, Hindus, Hindi and senior citizens - all are suffering.

Dr.MAHESH K MANDHYANI

4 months ago

WE ALL SHOULD SUPPORT SUCH ILLEGAL ACTIVITIES AROUND US.

D S Ranga Rao

4 months ago

''................however, no VIPs were reportedly involved in the accident.........'' used to be the refrain of the news reporters and officials which used to comfort the government whenever a major accident happens. So, illegal sand mining or any other illegal activity that always costs the lives of innocent poor people does not matter to government that is full of irresponsible and unaccountable public servants.

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