Leisure, Lifestyle & Wellness
New therapy speeds up wound healing
People can soon cut down the time taken to heal their everyday cuts and burns by half with the help of a new therapy developed by researchers at the Albert Einstein College of Medicine of Yeshiva University here.
 
Details of the therapy, which was successfully tested in mice, were published online in the Journal of Investigative Dermatology.
 
"We envision that our nanoparticle therapy could be used to speed the healing of all sorts of wounds, including everyday cuts and burns, surgical incisions, and chronic skin ulcers, which are a particular problem in the elderly and people with diabetes," said study co-leader David Sharp, professor of physiology & biophysics at Einstein.
 
The researchers discovered that an enzyme called fidgetin-like 2 (FL2) puts the brakes on skin cells as they migrate towards wounds to heal them.
 
They reasoned that the healing cells could reach their destination faster if their levels of FL2 could be reduced.
 
So they developed a drug that inactivates the gene that makes FL2 and then put the drug in tiny gel capsules called nanoparticles and applied the nanoparticles to wounds on mice.
 
The treated wounds healed much faster than untreated wounds.
 
FL2 belongs to the fidgetin family of enzymes, which play varying roles in cellular development and function.
 
To learn more about FL2's role in humans, Sharp suppressed FL2's activity in human cells in tissue culture. When those cells were placed on a standard wound assay (for measuring properties like cell migration and proliferation), they moved unusually fast.
 
"This suggested that if we could find a way to target FL2 in humans, we might have a new way to promote wound healing," Sharp said.

User

Possibility of truce with Yadav, Bhushan remote: Ashutosh
Aam Aadmi Party (AAP) leader Ashutosh on Friday said the possibility of a truce with dissident leaders Yogendra Yadav and Prashant Bhushan was "remote".
 
"To be honest and frank, the possibility of truce or peace is remote because they (Bhushan and Yadav) are insisting on removal of Kejriwal (as national convener) which is not possible," Ashutosh told a news channel.
 
"If you are part of a party, you have to accept its leader," he added.
 
Less than two months after it stormed to power in Delhi, the AAP on Thursday that Bhushan and Yadav had quit as its national executive. The duo fervently denied it.
 
AAP spokesman Ashish Khetan said the two leaders were dead set against Delhi Chief Minister Arvind Kejriwal, the party's best known face, who assumed office on February 14.

User

Conflicted Advice
Be wary of hidden commissions behind ‘advice’
 
If you are seeking financial advice,...
Premium Content
Monthly Digital Access

Subscribe

Already A Subscriber?
Login
Yearly Digital+Print Access

Subscribe

Moneylife Magazine Subscriber or MSSN member?
Login

Yearly Subscriber Login

Enter the mail id that you want to use & click on Go. We will send you a link to your email for verficiation

We are listening!

Solve the equation and enter in the Captcha field.
  Loading...
Close

To continue


Please
Sign Up or Sign In
with

Email
Close

To continue


Please
Sign Up or Sign In
with

Email

BUY NOW

The Scam
24 Year Of The Scam: The Perennial Bestseller, reads like a Thriller!
Moneylife Magazine
Fiercely independent and pro-consumer information on personal finance
Stockletters in 3 Flavours
Outstanding research that beats mutual funds year after year
MAS: Complete Online Financial Advisory
(Includes Moneylife Magazine and Lion Stockletter)