The Bollywood legend, who appeared in over 180 films in his career spanning more than four decades, says he never paid attention to his popularity
Mumbai: Megastar Amitabh Bachchan, who turned 70 on Thursday, says he never cared about his popularity but believed that one's outlook towards life matters the most, reports PTI.
"Every human being will go through a phase when there are highs and lows. Everything that goes up also comes down. I don't think I am particularly different from anyone. We all have our highs and lows. It is just about what kind of attitude you have during the time," Bachchan told PTI in an interview.
"If you have success, you should know that it is going to be short lived and if you have lows and the courage to fight or an attempt to make a comeback, then all the best," he added.
The Bollywood legend, who has appeared in over 180 films in his career spanning more than four decades, says his contemporary actors too are doing well in their capacity.
"I never judge myself. I cannot say my contemporaries have been left behind me. That would be wrong. I have never paid attention to my popularity. People can write what they want to but it doesn't matter to me," he said.
Bachchan said actors like Shatrughan Sinha, Vinod Khanna, Dharmendra and Rishi Kapoor are "very much active" and working in films.
"Unfortunately, Shashi Kapoor is unwell or else I am sure he too would be active.
"In fact, Vinod Khanna and Shatrughan Sinha have entered politics and are doing well... I feel I have been left behind by my contemporaries," he said.
Bachchan, who acted only once with Dilip Kumar on screen- in 1982 hit 'Shakti', says the acting great is his idol.
"Dilip saab and Waheedaji (Waheeda Rehman) are my favourite artists of all time and my idols even today. When it comes to the history of Indian cinema, I believe it can be easily divided into an era before Dilip Kumar, and after he joined films. There cannot be anyone like him," he said.
"When you get to work with someone who has been your favourite actor or the one you idolise, there are a lot of emotions that run through your mind. He is someone whom I have looked up to him since my childhood," he said.
Recalling shooting of 'Shakti', Bachchan said, "When we came together to shoot I felt bizarre. It was difficult for me to digest the fact that I was sharing screen space with Dilip Kumar. I am fortunate enough to have got the opportunity to work with a legendary actor like him. I am still in constant touch with Dilipsaab."
Bachchan said he was fortunate to have got the opportunity to work with a range of directors but considers Hrishikesh Mukherjee as his "godfather".
"I am thankful to Khwaja Ahmad Abbas, who gave me my first film (Saat Hindustani). I consider Hrishikesh Mukherjee as my godfather. We shared a close bond. Everyone feels I have done more films with Prakash Mehra and Manmohan Desai but that is not true, I have done more films with Hrishida," Bachchan said.
"Manmohan Desai had madness in him. He knew the pulse of the audience very well. Yash Chopra gave some of the biggest hits of my career. At the same time, I worked with Mukul Anand and Tinnu Anand," he said.
Bachchan praised filmamkers Karan Johar, Prakash Jha, Sanjay Leela Bhansali and Shoojit Sircar among others.
"The new millennium saw the rise of filmmakers like Aditya Chopra and Karan Johar and I was fortunate to work with them. At this time in my career, I am working once again with some bright filmmakers like R Balki, Shoojit Sircar and Prakash Jha, who have brilliant ideas," the veteran actor said.
Bachhan also has a word of praise for current crop of films.
"There have been some brilliant films like 'Paan Singh Tomar', 'Gangs Of Wasseypur', 'Vicky Donor', and 'Kahaani'. These films are so different and liked by almost everyone. They did good business too. This shows the audience has matured and wants a good story with good presentation," he said.
A string of celebrities from the world of marquee, including south actors Rajanikanth and Chiranjeevi among others, besides corporate bigwigs Anil Ambani, Kumar Mangalam Birla wished the actor on his birthday in advance at Film City last night.
The veteran actor's career spanning over four decades has progressed through many ups and downs.
Bachchan, whose baritone is one of his USPs, initially faced rejection for it during his struggling years.
Though he made his acting debut through 'Saat Hindustani' in 1969, the 1973 blockbuster 'Zanjeer' established his famous 'angry young man' image followed by Hrishkesh Mukherjee's 'Anand' where he shared the screen space with Rajesh Khanna.
Big B's rise to super-stardom continued with hits like 'Namak Haram', 'Deewar', 'Sholay', 'Trishul', 'Don', 'Kabhie Kabhie', 'Silsila', and 'Yaraana'.
In 1984, Bachchan took a break from acting and briefly entered politics. He became a Congress MP from Allahabad seat. However, he soon left the politics.
During 1988-92 he gave films like 'Shahanshah', 'Hum' 'Agnipath', 'Khuda Gawah' to name a few.
He founded Amitabh Bachchan Corporation Ltd (ABCL) in 1996, which was later mired in financial crisis.
In 2000, Bachchan appeared in Yash Chopra's 'Mohabbatein'.
He played role of an old, stern figure which won him the third 'Filmfare Best Supporting Actor Award'. He continued performing in a number of films.
In 2007, Bachchan made a debut appearance in an English-language film, Rituparno Ghosh's 'The Last Lear'. He also acted in films based on variety of themes like 'Bhootnath', 'Sarkar Raj', 'Paa'.
Bachchan was slated to play a supporting role in his first international film, 'Shantaram', directed by Mira Nair and starring Hollywood actor Johnny Depp in the lead but the project could not take off.
Big B's television career was equally illustrious with popular quiz show 'Kaun Banega Crorepati' the Indian adaptation of British show 'Who Wants to be a Millionaire?'
Drugs produced at 'compounding' pharmacies - like the steroids suspected of 12 meningitis deaths - are exempt from the safety checks that mass-produced pharmaceuticals receive
Imagine my surprise when I heard about Vegas Mixx, the latest club drug being promoted in Las Vegas. Marketing materials described it as a combination of Valium, to relax the mind, and Viagra, to stimulate the, well, you know. Vegas Mixx promised to make users perform “Like a Porn Star.”
I’m no medical expert, but this didn’t sound like a good idea. Valium, a controlled substance, can have serious side effects. And Viagra, well, warnings about erections lasting longer than four hours should give anyone pause.
Was it legal? When I was a reporter at the Las Vegas Sun, the guys running the local compounding pharmacy that made Vegas Mixx had no problem telling me they were just trying to make a buck. They claimed it was legal. And indeed, the pharmacy never was disciplined by the Nevada State Board of Pharmacy. They only stopped producing the drug because it wasn’t profitable.
Vegas Mixx turned out to be a bust. But it highlighted an evolution in the drug compounding industry, which has come under intense scrutiny after steroids produced by a Massachusetts company were linked to 12 fungal meningitis deaths and 137 infections in 10 states. The New England Compounding Center, which made the injectable steroids linked to the outbreak, acted more like a drug manufacturer than a traditional compounding pharmacy, said David Miller, executive vice president and CEO of the International Academy of Compounding Pharmacies.
Compounding pharmacies typically provide custom-made drugs based on individual physician prescriptions tailored to specific patients, who, for example, might be allergic to a mass-produced product. In contrast, the compounding pharmacy that made Vegas Mixx was making and marketing a drug combo before a doctor had prescribed it. The New England Compounding Center shipped more than 17,000 doses of steroid injections to 23 states, according to the Centers for Disease Control.
Those steroid doses, and other concoctions by compounding pharmacies, are exempt from traditional review and approvalby the Food and Drug Administration, which is charged with assuring the efficacy, purity and safety of manufactured drug compounds and strict adherence to sanitary manufacturing standards.
An FDA official said in an email that state pharmacy boards are the front lines of enforcing the activities of compounding pharmacies. The FDA can step in, but there have been conflicting court rulings about how federal law applies to compounding pharmacies, the FDA official said. That means compounding pharmacies operating as manufacturers are below the radar of FDA oversight, Miller said, potentially putting patients at risk.
This could have been prevented. More than a decade ago, David Kessler, former FDA commissioner, issued a warning about the future of compounded drugs at a Congressional hearing prior to passage of the Food and Drug Administration Modernization Act of 1997. He said that ambiguity in the law could allow for “large scale manufacturing under the guise of pharmacy compounding,” leading to a “shadow industry” of unapproved generic drugs.
Provisions in the act designed to clarify FDA oversight of compounding pharmacies — including restrictions on their ability to advertise drugs — were later struck down by courts. Still, the FDA says it can act in some circumstances, such as when a drug is contaminated or mislabeled.
Miller said he believes only a few rogue compounding pharmacies are operating outside traditional boundaries. The New England Compounding Center “appears to have been acting as a manufacturer without being registered as a manufacturer with the (Food and Drug Administration), or registering with the Massachusetts Board of Pharmacy as a manufacturer,” he said.
“Something does need to change. That’s something our association is grappling with right now,” he said. In the wake of the outbreak, officials from the academy are in contact with congressional staffers to discuss how to increase oversight without stifling traditional pharmacy practices, Miller added.
Other cases have raised alarms. In 2007, a Portland Tribune investigation revealed patient deaths that were linked to a bad batch of drugs, used to treat back pain, from a Texas compounding pharmacy. A pharmacist who consults with the advocacy group Public Citizen called the compounding pharmacy industry a “shadow drug industry,” in an interview with the newspaper.
And this week the Tennessee attorney general filed a complaint against HRC Medical Center, a hormone replacement therapy company that used a compounding pharmacy to produce the testosterone pellets for women. In the past year, I interviewed several women who were treated at HRC facilities, and they complained of testosterone treatments that led to excess facial hair, uncontrollable rage and genital growth. One doctor who reviewed an HRC patient’s medical records on behalf of ProPublica said her testosterone levels were more than four times normal – into the range of a man.
It's unknown whether the alleged problems at HRC Medical were caused by the providers, by the pharmacy, or both. Officials from HRC Medical did not return calls for comment. But according to the attorney general’s complaint, the hormone pellets the compounding pharmacy supplied to HRC Medical could trigger an unpredictable release of hormones in the blood stream due to their unproven method of manufacturing. The pharmacy's production standards, material handling practices and operating procedures were not FDA approved, the complaint stated.
Miller said responsibility for the fungal meningitis outbreak goes beyond the compounding pharmacy involved and regulatory gaps. Doctors and medical providers purchased the drugs and should also be held accountable for the patient harm, he said.
“What due diligence did those facilities do to assure the drugs they were purchasing were appropriate, safe and effective?” he asked.
Sagar Atre of ProPublica contributed reporting to this story.
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